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Accutane
 Accutane (Istetinoin)
Accutane
is one of the branded names for isotretinoin and is a
naturally occurring derivative of vitamin A. Accutane or
isotretinoin helps in reducing the amount of oil released by oil glands
of your skin and aids the skin in repairing itself more quickly.
Basically, the drug is used to treat severe nodular acnes.
Traditionally, it was utilized when other acne medicines or antibiotics
failed in the treatment of symptoms.
Isotretinoin is marketed
under several brand names by various manufacturers. You can buy the
drug in form of 5 mg, 10 mg,
20 mg, 30 mg
and 40 mg capsules. Accure,
Accutane,
Aknenormin, Amnesteem,
Ciscutan, Clarus,
Isohexal, Istretinoin-A and
Sotret are some of the popular brands of
oral isotretinoin that are available in market.
The presence of Accutane
can be detected in the bloodstream of people. While it
has lots of side effects, but in some
ways it is safer than long-term antibiotic usage. Most of the
acne-controlling medicines are antibacterial agents, which are
effective only if used daily.
Being a naturally
occurring product, the body quickly removes isotretinoin from the
bloodstream if more serious problems occur and you stop taking it. Take
the drug with food and your body will absorb the medicine better and
faster.
Side
Effects/ Health Consequences:
Like its postive results,
the medicine also shows some negative side effects
among which some are common problems while some are severe, so keep you
should keep a check on these. The occurrence of ill-effects depend more
on the amount of dosage taken. If taken in lowest doses, there are
almost no side effects
at all.
Chapped lips, mild
nosebleeding, temporary hair thinning, rashes, dryness of nose,
headache, dry skin, itching, irritation of the eyelids and eyes, joint
and muscle pains, and intestinal and urinary symptoms are some of the
commonly reported ill-effects of Accutane.
Decreased night vision, depression and suicidal attempts may also occur
but not very often.
In addition, Accutane
can increase the level of blood fats, sometimes to risky
levels. But, the situtation can revert back to noraml condition once
you switch off the drug usage. Regular blood tests are necessary during
isotretinoin treatment.
However, the most
concerning and dangerous side effect of Accutane is
occurrence of serious birth defects if the drug is used by a pregnant
women. So, avoid consuming the drug during pregancy or consult your
doctor first.
Precautions
and Warnings:
If you are thinking of
using Accutane then it
is a must to have some knowledge of other important facts related to
the drug. You can buy Accutane
only after registering under a special program called “iPLEDGE.”
It is must to be registered in the program and sign documents to
understand the dangers of this medication.
It is dangerous to
purchase isotretinoin through internet sources or from vendors outside
the United States. The sale and distribution of the drug outside the
iPLEDGE program violates the rules and regulations of the
U.S. Food and Drug Administration.
The usage of the drug also
includes certain precautions and warnings that are beneficial for you.
Avoid using this medication if you experience allergic reactions or are
allergic to any food or drugs. Also don’t take Accutane in case you
have some heart disease, diabetes, asthma, liver disease, high
cholesterol, anorexia nervosa (an eating disorder), osteoporosis or
have a personal or family history of depression or mental illness. It
is a must for pregnant women to avoid taking this specific drug during
pregnancy. Stop using Accutane and
immediatley consult a doctor if you have unprotected sex or switching
off to your birth control pills or you think you might get pregnant.
Dosage:
The required dosage
of isotretinoin depends mainly on the weight of patients
and severity of their condition. High dose should not exceed beyond 2
mg/kg/day for a treatment period of 4–6 months. If you are willing to
start a second course then it may be used for two months following the
termination of the initial course. Various studies have showed that
lower dosage treatments are much more effective than higher ones.
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